Product details
Catalog number H0370753302.5G
Price for H0370753302.5G
Size / count 5 g
Amino acids linked to Polystyrene-2-chlorotrityl chloride resin. A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc strategy. Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro. This resin has also been used in the solid phase synthesis of ß-peptides via the Arndt-Eistert homologation of Fmoc-protected amino acid diazoketones. Cleavage from this resin is achieved for protected peptides by treatment either with AcOH/trifluoroethanol/DCM or 0.5% TFA in DCM or hexafluoroisopropanol. Free peptides are released with 95% TFA. Fmoc D-amino acids on request
The catalog number for H-Arg (Pbf) -2-CT Polystyrene Resin is H0370753302.5G.
H-Arg (Pbf) -2-CT Polystyrene Resin is available in the following size(s): 5 g.
H-Arg (Pbf) -2-CT Polystyrene Resin is currently made to order / not held in immediate stock. Contact us for lead time.
Amino acids linked to Polystyrene-2-chlorotrityl chloride resin. A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc strategy. Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin with
Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.