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Product details

H-Arg (Pbf) -2-CT Polystyrene Resin

Catalog number H0370753302.25G

Price for H0370753302.25G

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Size / count 25 g

About this product

Amino acids linked to Polystyrene-2-chlorotrityl chloride resin. A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc strategy. Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro. This resin has also been used in the solid phase synthesis of ß-peptides via the Arndt-Eistert homologation of Fmoc-protected amino acid diazoketones. Cleavage from this resin is achieved for protected peptides by treatment either with AcOH/trifluoroethanol/DCM or 0.5% TFA in DCM or hexafluoroisopropanol. Free peptides are released with 95% TFA. Fmoc D-amino acids on request

Specifications

Catalog number
H0370753302.25G
Size / count
25 g
Dry ice
No
Hazardous
No
Discontinued
No
Specifications
200 - 400 mesh
Capacity
0.4 - 1.2 mmol/g

Frequently Asked Questions

What is the catalog number for H-Arg (Pbf) -2-CT Polystyrene Resin?

The catalog number for H-Arg (Pbf) -2-CT Polystyrene Resin is H0370753302.25G.

What sizes are available for H-Arg (Pbf) -2-CT Polystyrene Resin?

H-Arg (Pbf) -2-CT Polystyrene Resin is available in the following size(s): 25 g.

Is H-Arg (Pbf) -2-CT Polystyrene Resin in stock?

H-Arg (Pbf) -2-CT Polystyrene Resin is currently made to order / not held in immediate stock. Contact us for lead time.

What is H-Arg (Pbf) -2-CT Polystyrene Resin used for?

Amino acids linked to Polystyrene-2-chlorotrityl chloride resin. A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc strategy. Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin with

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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