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Product details

H-Nle-2-CT Polystyrene Resin

Catalog number H0370753319.5G

Price for H0370753319.5G

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Size / count 5 g

About this product

Amino acids linked to Polystyrene-2-chlorotrityl chloride resin. A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc strategy. Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro. This resin has also been used in the solid phase synthesis of ß-peptides via the Arndt-Eistert homologation of Fmoc-protected amino acid diazoketones. Cleavage from this resin is achieved for protected peptides by treatment either with AcOH/trifluoroethanol/DCM or 0.5% TFA in DCM or hexafluoroisopropanol. Free peptides are released with 95% TFA. Fmoc D-amino acids on request

Specifications

Catalog number
H0370753319.5G
Size / count
5 g
Dry ice
No
Hazardous
No
Discontinued
No
Specifications
200 - 400 mesh
Capacity
0.4 - 1.2 mmol/g

Frequently Asked Questions

What is the catalog number for H-Nle-2-CT Polystyrene Resin?

The catalog number for H-Nle-2-CT Polystyrene Resin is H0370753319.5G.

What sizes are available for H-Nle-2-CT Polystyrene Resin?

H-Nle-2-CT Polystyrene Resin is available in the following size(s): 5 g.

Is H-Nle-2-CT Polystyrene Resin in stock?

H-Nle-2-CT Polystyrene Resin is currently made to order / not held in immediate stock. Contact us for lead time.

What is H-Nle-2-CT Polystyrene Resin used for?

Amino acids linked to Polystyrene-2-chlorotrityl chloride resin. A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc strategy. Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin with

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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