Product details
Catalog number H0751503307.25G
Price for H0751503307.25G
Size / count 25 g
Amino acids linked to Polystyrene-2-chlorotrityl chloride resin. A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc strategy. Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro. This resin has also been used in the solid phase synthesis of ß-peptides via the Arndt-Eistert homologation of Fmoc-protected amino acid diazoketones. Cleavage from this resin is achieved for protected peptides by treatment either with AcOH/trifluoroethanol/DCM or 0.5% TFA in DCM or hexafluoroisopropanol. Free peptides are released with 95% TFA. Fmoc D-amino acids on request
The catalog number for H-Cys (Acm) -2-CT Polystyrene Resin is H0751503307.25G.
H-Cys (Acm) -2-CT Polystyrene Resin is available in the following size(s): 25 g.
H-Cys (Acm) -2-CT Polystyrene Resin is currently made to order / not held in immediate stock. Contact us for lead time.
Amino acids linked to Polystyrene-2-chlorotrityl chloride resin. A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc strategy. Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin with
Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.
Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.