Product details
Catalog number SAD1215.5G
Price for SAD1215.5G
Size / count 5 g
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. The graft copolymer shows modified physicochemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix) and has hydrophobic and hydrophilic properties. These copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions.The PEG spacer is in the range of MW 3000 Da. TentaGel® resins have high diffusion rates and excellent swelling in a wide range of solvents from e.g. toluene to water. Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro. This resin is recommended for synthesis of standard peptides up to 40 residues in length. The sensitivity towards TFA is comparable to the 2-CT linker. Cleavage can be achieved with 50% AcOH in CH₂Cl₂ to liberate protected peptides. For free peptides 95% TFA is afforded.
The catalog number for Fmoc-D-Ile TentaGel® S TRT Resin is SAD1215.5G.
Fmoc-D-Ile TentaGel® S TRT Resin is available in the following size(s): 5 g.
Fmoc-D-Ile TentaGel® S TRT Resin is currently made to order / not held in immediate stock. Contact us for lead time.
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. The graft copolymer shows modified physicochemical pro
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Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.