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Product details
Catalog number 1320000-00-50.500MG
Price for 1320000-00-50.500MG
Size / count 500 mg
PEGs with an active ester functional group at one end allow for selective and covalent attachment to other molecules with complementary functional groups, such as primary amines on proteins, peptides, or other molecules. To a lesser extent they are reactive towards thiols or hydroxyls (to form thioesters or esters) . Squaric Acid Ester Amido PEGs are a novel class of reactive and chemoselective PEG crosslinking reagents. The squaric acid PEGs are chemoselective towards the amino groups of Lysin in protein PEGylation whereas the guanidine function of Arginine, the hydroxyl group of Serine and the imidazole function of Histidine are not affected. Compared to other active esters, these PEGs are remarkably stable in aqueous media and not easily hydrolyzed. The hydroxy group on one side of this PEG crosslinker is able to undergo esterification reactions with acids for reversible pegylation. It also enables further derivatization or replacement with other reactive functional groups.
The catalog number for Ɑ-Hydroxy-ω-Squaric Acid Ester Amido PEG is 1320000-00-50.500MG.
Ɑ-Hydroxy-ω-Squaric Acid Ester Amido PEG is available in the following size(s): 500 mg.
Ɑ-Hydroxy-ω-Squaric Acid Ester Amido PEG is currently made to order / not held in immediate stock. Contact us for lead time.
PEGs with an active ester functional group at one end allow for selective and covalent attachment to other molecules with complementary functional groups, such as primary amines on proteins, peptides, or other molecules. To a lesser extent they are reactive towards thiols or hydroxyls (to form thioe
Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.
