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Product details
Catalog number 133000-00-50.500MG
Price for 133000-00-50.500MG
Size / count 500 mg
PEGs with an active ester functional group at one end allow for selective and covalent attachment to other molecules with complementary functional groups, such as primary amines on proteins, peptides, or other molecules. To a lesser extent they are reactive towards thiols or hydroxyls (to form thioesters or esters) . Squaric Acid Ester Amido PEGs are a novel class of reactive and chemoselective PEG crosslinking reagents. The squaric acid PEGs are chemoselective towards the amino groups of Lysin in protein PEGylation whereas the guanidine function of Arginine, the hydroxyl group of Serine and the imidazole function of Histidine are not affected. Compared to other active esters, these PEGs are remarkably stable in aqueous media and not easily hydrolyzed. The hydroxy group on one side of this PEG crosslinker is able to undergo esterification reactions with acids for reversible pegylation. It also enables further derivatization or replacement with other reactive functional groups.
The catalog number for Ɑ-Hydroxy-ω-Squaric Acid Ester Amido PEG is 133000-00-50.500MG.
Ɑ-Hydroxy-ω-Squaric Acid Ester Amido PEG is available in the following size(s): 500 mg.
Ɑ-Hydroxy-ω-Squaric Acid Ester Amido PEG is currently made to order / not held in immediate stock. Contact us for lead time.
PEGs with an active ester functional group at one end allow for selective and covalent attachment to other molecules with complementary functional groups, such as primary amines on proteins, peptides, or other molecules. To a lesser extent they are reactive towards thiols or hydroxyls (to form thioe
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
