- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
Select the image to view it full size.
Product details
Catalog number 133000-65-32.500MG
Price for 133000-65-32.500MG
Size / count 500 mg
This PEG linker with a maleimide endgroup is applied in sulfhydryl-selective coupling of PEG to proteins and other thiol substrates and for selective scavenging of thiol containing peptides. The maleimide group reacts at about neutral pH with free thiols via a Michael addition to form a stable thioether bond. Carboxy PEGs may be used for conjugation to amine substrates (forming amides) or other nucleophiles (forming esters) . However, activation is necessary prior to conjugation. Different PEG carboxy derivatives display a different degree of stability and reactivity of the corresponding active ester. The butyric acid endgroup is directly connected to the PEG chain via a very stable ether linkage. After activation it is used to conjugate the PEG derivative to nucleophilic substrates, mainly amines (to form amides) or hydroxyls/thiols (forming esters) . PEG butyric acid active esters are one of the most hydrolytically stable PEG active esters. They can be used for pegylation in aqueous media without the need of a large excess of PEG.
The catalog number for Ɑ-Butyric Acid-ω-Maleimidohexanamido PEG is 133000-65-32.500MG.
Ɑ-Butyric Acid-ω-Maleimidohexanamido PEG is available in the following size(s): 500 mg.
Ɑ-Butyric Acid-ω-Maleimidohexanamido PEG is currently made to order / not held in immediate stock. Contact us for lead time.
This PEG linker with a maleimide endgroup is applied in sulfhydryl-selective coupling of PEG to proteins and other thiol substrates and for selective scavenging of thiol containing peptides. The maleimide group reacts at about neutral pH with free thiols via a Michael addition to form a stable thioe
Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.
The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.
Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.
