Product details
Catalog number 112000-44.1G
Price for 112000-44.1G
Size / count 1 g
The OPSS functional group at each end of the PEG linker molecule allows selective and reversible attachment to other molecules with complementary functional groups, such as thiol groups on proteins or peptides. This can be achieved through thiol-disulfide exchange reactions, which result in the formation of disulfide linkages between the two molecules. Another possible application includes the formation of free thiols in solution and subsequent pegylation of transition metal surfaces. PEG linker molecules with OPSS endgroups are particularly useful for the reversible PEGylation of proteins and peptides, as the disulfide bond formed between the OPSS group and the thiol group of the substrate can be cleaved under reducing conditions, such as with the addition of a reducing agent like dithiothreitol (DTT) or tris (2-carboxyethyl) phosphine (TCEP) . This allows the recovery of the unmodified protein or peptide, which can be useful in certain applications.
The catalog number for α, ω-Bis-Pyridyldithio PEG is 112000-44.1G.
α, ω-Bis-Pyridyldithio PEG is available in the following size(s): 1 g.
α, ω-Bis-Pyridyldithio PEG is currently made to order / not held in immediate stock. Contact us for lead time.
The OPSS functional group at each end of the PEG linker molecule allows selective and reversible attachment to other molecules with complementary functional groups, such as thiol groups on proteins or peptides. This can be achieved through thiol-disulfide exchange reactions, which result in the form
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.