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Product details
Catalog number 112000-44.5G
Price for 112000-44.5G
Size / count 5 g
The OPSS functional group at each end of the PEG linker molecule allows selective and reversible attachment to other molecules with complementary functional groups, such as thiol groups on proteins or peptides. This can be achieved through thiol-disulfide exchange reactions, which result in the formation of disulfide linkages between the two molecules. Another possible application includes the formation of free thiols in solution and subsequent pegylation of transition metal surfaces. PEG linker molecules with OPSS endgroups are particularly useful for the reversible PEGylation of proteins and peptides, as the disulfide bond formed between the OPSS group and the thiol group of the substrate can be cleaved under reducing conditions, such as with the addition of a reducing agent like dithiothreitol (DTT) or tris (2-carboxyethyl) phosphine (TCEP) . This allows the recovery of the unmodified protein or peptide, which can be useful in certain applications.
The catalog number for α, ω-Bis-Pyridyldithio PEG is 112000-44.5G.
α, ω-Bis-Pyridyldithio PEG is available in the following size(s): 5 g.
α, ω-Bis-Pyridyldithio PEG is currently made to order / not held in immediate stock. Contact us for lead time.
The OPSS functional group at each end of the PEG linker molecule allows selective and reversible attachment to other molecules with complementary functional groups, such as thiol groups on proteins or peptides. This can be achieved through thiol-disulfide exchange reactions, which result in the form
As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.
Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.
Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.
