- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
Select the image to view it full size.
Product details
Catalog number 1120000-44.1G
Price for 1120000-44.1G
Size / count 1 g
The OPSS functional group at each end of the PEG linker molecule allows selective and reversible attachment to other molecules with complementary functional groups, such as thiol groups on proteins or peptides. This can be achieved through thiol-disulfide exchange reactions, which result in the formation of disulfide linkages between the two molecules. Another possible application includes the formation of free thiols in solution and subsequent pegylation of transition metal surfaces. PEG linker molecules with OPSS endgroups are particularly useful for the reversible PEGylation of proteins and peptides, as the disulfide bond formed between the OPSS group and the thiol group of the substrate can be cleaved under reducing conditions, such as with the addition of a reducing agent like dithiothreitol (DTT) or tris (2-carboxyethyl) phosphine (TCEP) . This allows the recovery of the unmodified protein or peptide, which can be useful in certain applications.
The catalog number for α, ω-Bis-Pyridyldithio PEG is 1120000-44.1G.
α, ω-Bis-Pyridyldithio PEG is available in the following size(s): 1 g.
α, ω-Bis-Pyridyldithio PEG is currently made to order / not held in immediate stock. Contact us for lead time.
The OPSS functional group at each end of the PEG linker molecule allows selective and reversible attachment to other molecules with complementary functional groups, such as thiol groups on proteins or peptides. This can be achieved through thiol-disulfide exchange reactions, which result in the form
Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.
Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
