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Product details
Catalog number 113000-44.5G
Price for 113000-44.5G
Size / count 5 g
The OPSS functional group at each end of the PEG linker molecule allows selective and reversible attachment to other molecules with complementary functional groups, such as thiol groups on proteins or peptides. This can be achieved through thiol-disulfide exchange reactions, which result in the formation of disulfide linkages between the two molecules. Another possible application includes the formation of free thiols in solution and subsequent pegylation of transition metal surfaces. PEG linker molecules with OPSS endgroups are particularly useful for the reversible PEGylation of proteins and peptides, as the disulfide bond formed between the OPSS group and the thiol group of the substrate can be cleaved under reducing conditions, such as with the addition of a reducing agent like dithiothreitol (DTT) or tris (2-carboxyethyl) phosphine (TCEP) . This allows the recovery of the unmodified protein or peptide, which can be useful in certain applications.
The catalog number for α, ω-Bis-Pyridyldithio PEG is 113000-44.5G.
α, ω-Bis-Pyridyldithio PEG is available in the following size(s): 5 g.
α, ω-Bis-Pyridyldithio PEG is currently made to order / not held in immediate stock. Contact us for lead time.
The OPSS functional group at each end of the PEG linker molecule allows selective and reversible attachment to other molecules with complementary functional groups, such as thiol groups on proteins or peptides. This can be achieved through thiol-disulfide exchange reactions, which result in the form
Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.
Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.
