ESD Recombinant Mouse Monoclonal Antibody [J0-8-R]

Catalog number HA601305

Price for HA601305

Size / count 100 µL

About this product

ESD (esterase D) is also known as S-formylglutathione hydrolase and is a 282 amino acid protein that is a member of the esterase D family. ESD is highly expressed in placenta, kidney, liver and erythrocytes, and is localized to the cytoplasm, as well as to cytoplasmic vesicles. The main function of ESD is to detoxify formaldehyde while providing energy. Formaldehyde is oxidized by ADH5 which yields S-formylglutathione. ESD then catalyzes the hydrolysis of S-formylglutathione to the reduced forms of formic acid and glutathione. In addition, ESD hydrolyzes a variety of different neutral ester substrates and can act as a carboxylesterase. ESD may also act as a cysteine hydrolase which is inactivated by thiol alkylating agents. ESD gene polymorphism can lead to reduced enzymatic activity which may cause susceptibility to many conditions, including toxic liver cirrhosis, retinoblastoma, obesity and autism.

Specifications

Catalog number: HA601305
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: EC 3.1.2.12 antibody Es-10 antibody Es10 antibody ESD antibody ESTD_HUMAN antibody Esterase 10 antibody Esterase D antibody Esterase D formylglutathione hydrolase antibody FGH antibody FGH, included antibody FLJ11763 antibody Methylumbelliferyl acetate deacetylase antibody MGC139609 antibody OTTHUMP00000018374 antibody OTTHUMP00000040929 antibody S formylglutathione hydrolase antibody S-formylglutathione hydrolase antibody S-formylglutathione hydrolase, included antibody Sid 478 antibody sid478 antibody
Abbreviation: FGH
Swiss Prot: P10768 Human, Q9R0P3 Mouse, B0BNE5 Rat
Cellular Locus: Cytoplasm. Cytoplasmic vesicle.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human ESD aa 1-182 / 282.
Isotype: IgG1
Clone: J0-8-R
Conjugation: Non-conjugated
Type: Recombinant Mouse monoclonal Antibody
Applications: WB
Positive Control: K-562 cell lysate, Jurkat cell lysate, HeLa cell lysate, HepG2 cell lysate, SW480 cell lysate, human kidney tissue lysate, mouse kidney tissue lysate, mouse colon tissue lysate, mouse stomach tissue lysate, rat kidney tissue lysate, rat colon tissue lysate, rat stomach tissue lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:20,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 31 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for ESD Recombinant Mouse Monoclonal Antibody [J0-8-R]?

The catalog number for ESD Recombinant Mouse Monoclonal Antibody [J0-8-R] is HA601305.

What sizes are available for ESD Recombinant Mouse Monoclonal Antibody [J0-8-R]?

ESD Recombinant Mouse Monoclonal Antibody [J0-8-R] is available in the following size(s): 100 µL.

Is ESD Recombinant Mouse Monoclonal Antibody [J0-8-R] in stock?

ESD Recombinant Mouse Monoclonal Antibody [J0-8-R] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ESD Recombinant Mouse Monoclonal Antibody [J0-8-R] used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.