CD11b Recombinant Rabbit Monoclonal Antibody [JE01-17]

Catalog number HA722856

Price for HA722856

Size / count 100 µL

About this product

Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens 1, 2. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration 3. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils 4. May regulate phagocytosis-induced apoptosis in extravasated neutrophils (By similarity). May play a role in mast cell development (By similarity). Required with TYROBP/DAP12 in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development (By similarity).

Specifications

Catalog number: HA722856
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: antigen CD11b (p170) Antigen CD11b p170 CD11 antigen like family member B CD11 antigen-like family member B CD11b CD11b/CD18 CD49d Cell surface glycoprotein MAC-1 subunit alpha Complement component 3 receptor 3 subunit Complement Component Receptor 3 Alpha Complement receptor type 3 Complement receptor type 3, alpha subunit CR 3 alpha chain CR 3 alpha chain (CR3A) CR-3 alpha chain CR3 CR3A F730045J24Rik Integrin Alpha M Integrin alpha M chain Integrin alpha-M Integrin beta 2 alpha subunit Integrin subunit alpha M integrin, alpha M (complement component 3 receptor 3 subunit) ITAM_HUMAN ITGAM Leukocyte adhesion receptor MO1 Ly-40 MAC 1 Mac-1a MAC1 Mac1, alpha subunit MAC1A Macrophage antigen alpha polypeptide MGC117044 Mo1 Mo1, alpha subunit MO1A Neutrophil adherence receptor Neutrophil adherence receptor alpha M subunit SLEB6
Abbreviation: CD11B, CR3A, MAC-1
Swiss Prot: P11215 Human, P05555 Mouse,
Cellular Locus: Cell membrane, Membrane raft.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide.
Isotype: IgG
Clone: JE01-17
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-Fr, IHC-P, IF-Tissue
Positive Control: RAW264.7 cell lysate, J774A.1 cell lysate, Mouse spleen tissue lysate, Rat spleen tissue lysate, human cevical cancer tissue, human slpeen tissue, human tonsil tissue, mouse spleen tissue, rat spleen tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IHC-Fr: 1:500 ;IHC-P: 1:2,000-1:5,000 ;IF-Tissue: 1:500-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 127 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for CD11b Recombinant Rabbit Monoclonal Antibody [JE01-17]?

The catalog number for CD11b Recombinant Rabbit Monoclonal Antibody [JE01-17] is HA722856.

What sizes are available for CD11b Recombinant Rabbit Monoclonal Antibody [JE01-17]?

CD11b Recombinant Rabbit Monoclonal Antibody [JE01-17] is available in the following size(s): 100 µL.

Is CD11b Recombinant Rabbit Monoclonal Antibody [JE01-17] in stock?

CD11b Recombinant Rabbit Monoclonal Antibody [JE01-17] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD11b Recombinant Rabbit Monoclonal Antibody [JE01-17] used for?

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

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Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.