Anti-HOXA10 Antibody Picoband®

About this product

Boster Bio Anti-HOXA10 Antibody Picoband® catalog # PB9217. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9217

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Homeobox protein Hox-A10 is a protein that in humans is encoded by the HOXA10 gene. HOXA10 is expressed in the adult human endometrium, and the expression of HOXA10 dramatically increased during the midsecretory phase of the menstrual cycle, corresponding to the time of implantation and increase in circulating progesterone. HOXA10 may have an important function in regulating endometrial development during the menstrual cycle and in establishing conditions necessary for implantation in the human. HOXA10 is also a master regulator of postnatal hematopoietic development whose tight regulation is required for normal development of erythroid and megakaryocytic lineages.

Synonyms

Homeobox protein Hox-A10; Homeobox protein Hox-1.8; Homeobox protein Hox-1H; PL; HOXA10; HOX1H

Gene Name

HOXA10

Gene ID

3206

UniProt

P31260

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human HOXA10 recombinant protein (Position: Y57-R340) . Human HOXA10 shares 87% amino acid (aa) sequence identity with mouse HOXA10.

Clonality

Polyclonal

Applications

WB

Field of Research

Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, Transcription

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'.

References & Citations

1. McAlpine PJ, Shows TB (Aug 1990) . Nomenclature for human homeobox genes. Genomics 7 (3) : 460. 2. Scott MP (Dec 1992) . Vertebrate homeobox gene nomenclature. Cell 71 (4) : 551–3. 3. Taylor, H. S., Arici, A., Olive, D., Igarashi, P. HOXA10 is expressed in response to sex steroids at the time of implantation in the human endometrium. J. Clin. Invest. 101: 1379-1384, 1998.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

42414 MW

Observed Molecular Weight

41 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Homeobox protein Hox-A10

Subcellular Location

Nucleus.

Sequence Similarities

Belongs to the Abd-B homeobox family.

Protein Name

Homeobox protein Hox-A10

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.