Anti-Fetuin A/AHSG Antibody Picoband®

About this product

Boster Bio Anti-Fetuin A/AHSG Antibody Picoband® catalog # PB9242. Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9242

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Alpha-2-HS-glycoprotein (AHSG) also known as fetuin-A is a protein that in humans is encoded by the AHSG gene. Fetuin-A belongs to the fetuin class of plasma binding proteins and is more abundant in fetal than adult blood. This gene is mapped to 3q27. Fetuin-A is a secreted partially phosphorylated glycoprotein with complex proeolytic processing that circulates in blood and extracellular fluids. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. Fetuin-A is also a potent inhibitor of pathological calcification.

Synonyms

Alpha-2-HS-glycoprotein; Countertrypin; Fetuin-A; Ahsg; Fetua

Gene Name

AHSG

Gene ID

11625

UniProt

P29699

Host

Rabbit

Reactivity

Mouse

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived mouse Fetuin A recombinant protein (Position: A19-I345) . Mouse Fetuin A shares 57% and 85% amino acid (aa) sequence identity with human and rat Fetuin A, respectively.

Clonality

Polyclonal

Tissue Specificity

Liver is the major site of synthesis, but fetuin is also expressed in limb buds and other extrahepatic tissues during development.

Applications

WB

Field of Research

Cardiovascular, Metabolism, Neurogenesis, Neurology Process, Neuroscience, Obesity, Serum Proteins

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Probably involved in differentiation.

References & Citations

1. Rizzu P, Baldini A (1995) . Three members of the human cystatin gene superfamily, AHSG, HRG, and KNG, map within one megabase of genomic DNA at 3q27. Cytogenet. Cell Genet. 70 (1-2) : 26–8. 2. Osawa M, Umetsu K, Sato M, Ohki T, Yukawa N, Suzuki T, Takeichi S (September 1997) . Structure of the gene encoding human alpha 2-HS glycoprotein (AHSG) . Gene 196 (1-2) : 121–5. 3. Entrez Gene: AHSG alpha-2-HS-glycoprotein

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

37326 MW

Observed Molecular Weight

55-60 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Alpha-2-HS-glycoprotein

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the fetuin family.

Protein Name

Alpha-2-HS-glycoprotein

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.