Anti-Prolactin/PRL Antibody Picoband®

About this product

Boster Bio Anti-Prolactin/PRL Antibody Picoband® catalog # PB9361. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9361

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Prolactin  (PRL), also known as luteotropic hormone or luteotropin, is a  protein  that in humans is best known for its role in enabling  female mammals to produce milk. This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein.

Synonyms

Prolactin; PRL; PRL

Gene Name

PRL

Gene ID

5617

UniProt

P01236

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Prolactin recombinant protein (Position: L29-227C) . Human Prolactin?shares?60%?and 63% amino?acid? (aa) ?sequence?identity?with mouse?and?rat Prolactin, respectively.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone- independent mammary carcinoma cell lines. .

Applications

ELISA, WB

Field of Research

Growth Factors/Hormones, Lipid Metabolism, Metabolism, Protein Phosphorylation, Receptor Tyrosine Kinases, Signal Transduction, Tyrosine Kinases

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Prolactin acts primarily on the mammary gland by promoting lactation.

References & Citations

1. Correale J, et al. Role of prolactin in B cell regulation in multiple sclerosis. J Neuroimmunol, 2014 Apr 15. 2. De Kuijper GM, et al. Effects of discontinuation of long-term used antipsychotics on prolactin and bone turnover markers in patients with intellectual disability. J Clin Psychopharmacol, 2014 Feb. 3. Zaga-Clavellina V, et al. The potential role of prolactin as a modulator of the secretion of proinflammatory mediators in chorioamniotic membranes in term human gestation. Am J Obstet Gynecol, 2014 Jul.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

25876 MW

Observed Molecular Weight

25 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Prolactin

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the somatotropin/prolactin family.

Protein Name

Prolactin

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.