Anti-Syndecan 4/SDC4 Antibody Picoband®

About this product

Boster Bio Anti-Syndecan 4/SDC4 Antibody Picoband® catalog # PB9388. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9388

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Syndecan 4 is also known as SDC4. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Synonyms

Syndecan-4; SYND4; Amphiglycan; Ryudocan core protein; SDC4

Gene Name

SDC4

Gene ID

6385

UniProt

P31431

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Syndecan 4, identical to the related mouse and rat sequences.

Clonality

Polyclonal

Tissue Specificity

Expressed in epithelial and fibroblastic cells. .

Applications

IHC, WB

Field of Research

Cell Adhesion Proteins, Cytoskeleton/ECM, ECM Proteins, Neurogenesis, Neurology Process, Neuroscience, Plasma Membrane, Signal Transduction, Subcellular Markers, Tags & Cell Markers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Cell surface proteoglycan that bears heparan sulfate.

References & Citations

1. Entrez Gene: SDC4 syndecan 4. 2. Woods A, Couchman JR (May 1998) . Syndecans: synergistic activators of cell adhesion. Trends Cell Biol. 8 (5) : 189–92.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

21642 MW

Observed Molecular Weight

22 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Syndecan-4

Subcellular Location

Isoform 1: Membrane; Single-pass type I membrane protein. Secreted. Shedding of the ectodomain produces a soluble form. .

Protein Name

Syndecan-4

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.