Anti-Wnt2 Antibody Picoband®

About this product

Boster Bio Anti-Wnt2 Antibody Picoband® catalog # PB9461. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9461

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

WNT2, also known as Wingless-type MMTV integration site family, member 2, is a human gene. This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene.

Synonyms

Protein Wnt-2; Int-1-like protein 1; Int-1-related protein; IRP; WNT2; INT1L1, IRP

Gene Name

WNT2

Gene ID

7472

UniProt

P09544

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Wnt2, different from the related mouse sequence by two amino acids.

Clonality

Polyclonal

Tissue Specificity

Expressed in brain in the thalamus, in fetal and adult lung and in placenta. .

Applications

WB

Field of Research

Cancer, Oncoproteins/Suppressors, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, Tumor Suppressors

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.

References & Citations

1. Entrez Gene: WNT2 wingless-type MMTV integration site family, member 2 2. Wainwright BJ, Scambler PJ, Stanier P, Watson EK, Bell G, Wicking C, Estivill X, Courtney M, Boue A, Pedersen PS (June 1988) . Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless. EMBO J. 7 (6) : 1743–8.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

40418 MW

Observed Molecular Weight

40 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Protein Wnt-2

Subcellular Location

Secreted, extracellular space, extracellular matrix.

Sequence Similarities

Belongs to the Wnt family.

Protein Name

Protein Wnt-2

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.