Anti-SOX5 Antibody Picoband®

About this product

Boster Bio Anti-SOX5 Antibody Picoband® catalog # PB9507. Tested in WB applications. This antibody reacts with Human, Mouse, Pig, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9507

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Transcription factor SOX-5 is a protein that in humans is encoded by the SOX5 gene. It is located on 12p12.1. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. In addition, the encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Synonyms

Transcription factor SOX-5; SOX5

Gene Name

SOX5

Gene ID

6660

UniProt

P35711

Host

Rabbit

Reactivity

Human, Mouse, Pig, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human SOX5, different from the related mouse sequence by two amino acids.

Clonality

Polyclonal

Tissue Specificity

Placenta, liver, and to a much smaller extent, in lung.

Applications

WB

Field of Research

Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, Transcription, Transcription Factors

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Binds specifically to the DNA sequence 5'-AACAAT-3'. Activates transcription of COL2A1 and AGC1 in vitro.

References & Citations

1. Entrez Gene: SOX5 SRY (sex determining region Y) -box 5. 2. Ikeda T; Zhang J; Chano T et al. (2003) . Identification and characterization of the human long form of Sox5 (L-SOX5) gene. Gene 298 (1) : 59–68. 3. Wunderle VM, Critcher R, Ashworth A, Goodfellow PN (Jan 1997) . Cloning and characterization of SOX5, a new member of the human SOX gene family. Genomics 36 (2) : 354–8.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

84026 MW

Observed Molecular Weight

84 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Transcription factor SOX-5

Subcellular Location

Nucleus .

Sequence Similarities

Contains 1 HMG box DNA-binding domain.

Protein Name

Transcription factor SOX-5

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.