Anti-G-CSF/CSF3 Antibody Picoband®

About this product

Boster Bio Anti-G-CSF/CSF3 Antibody Picoband® catalog # PB9563. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9563

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Granulocyte-colony stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream. Functionally, it is a cytokine and hormone, a type of colony-stimulating factor, and is produced by a number of different tissues. The pharmaceutical analogs of naturally occurring G-CSF are called filgrastim and lenograstim. G-CSF also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils.

Synonyms

Granulocyte colony-stimulating factor; G-CSF; Pluripoietin; Filgrastim; Lenograstim; CSF3; C17orf33, GCSF

Gene Name

CSF3

Gene ID

1440

UniProt

P09919

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E. coli-derived human G-CSF recombinant protein (Position: S38-P207) . Human G-CSF shares 76% amino acid (aa) sequence identity with mouse G-CSF.

Clonality

Polyclonal

Tissue Specificity

Non-neural epithelial tissues.

Applications

ELISA, IHC, WB

Field of Research

Angiogenesis, Cancer, Cytokines, Immunology, Innate Immunity, Invasion/Microenvironment

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.

References & Citations

1. Metcalf D (July 1985) . The granulocyte-macrophage colony-stimulating factors. Science 229 (4708) : 16–22. 2. Nagata S, Tsuchiya M, Asano S, Kaziro Y, Yamazaki T, Yamamoto O, Hirata Y, Kubota N, Oheda M, Nomura H (1986) . Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor. Nature 319 (6052) : 415–8. 3. Souza LM, Boone TC, Gabrilove J, Lai PH, Zsebo KM, Murdock DC, Chazin VR, Bruszewski J, Lu H, Chen KK, Barendt J, Platzer, E, Moore, MAS, Mertelsmann R, Welte K (April 1986) . Recombinant human granulocyte colony-stimulating factor: effects on normal and leukemic myeloid cells. Science 232 (4746) : 61–5.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

22293 MW

Observed Molecular Weight

22 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Granulocyte colony-stimulating factor

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the IL-6 superfamily.

Protein Name

Granulocyte colony-stimulating factor

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.