Anti-BMP5 Antibody Picoband®

About this product

Boster Bio Anti-BMP5 Antibody Picoband® catalog # PB9689. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9689

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Bone morphogenetic protein 5?is a?protein?that in humans is encoded by the?BMP5?gene. This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. And this protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.

Synonyms

Bone morphogenetic protein 5; BMP-5; BMP5

Gene Name

BMP5

Gene ID

653

UniProt

P22003

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human BMP-5, different from the related mouse sequence by three amino acids.

Clonality

Polyclonal

Tissue Specificity

Expressed in the lung and liver.

Applications

ELISA, Flow Cytometry, IHC, WB

Field of Research

Angiogenesis, Cardiovascular, Collagen, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Growth Factors, Growth Factors/Hormones, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, Structures, TGF Beta

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Induces cartilage and bone formation.

References & Citations

1. Entrez Gene: BMP5 bone morphogenetic protein 5. 2. Beck HN, Drahushuk K, Jacoby DB, Higgins D, Lein PJ (Mar 2003) . Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons. BMC Neurosci 2: 12. 3. Hahn GV, Cohen RB, Wozney JM, Levitz CL, Shore EM, Zasloff MA, Kaplan FS (Dec 1992) . A bone morphogenetic protein subfamily: chromosomal localization of human genes for BMP5, BMP6, and BMP7. Genomics 14 (3) : 759–62.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

51737 MW

Observed Molecular Weight

51 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Bone morphogenetic protein 5

Subcellular Location

Secreted.

Protein Name

Bone morphogenetic protein 5

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.