Anti-CD19 Antibody Picoband®

About this product

Boster Bio Anti-CD19 Antibody Picoband® catalog # PB9800. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9800

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

B-lymphocyte antigen CD19, also known as CD19 (Cluster of Differentiation 19), is a protein that in humans is encoded by the CD19 gene. It is found on the surface of B-cells, a type of white blood cell. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. The CD19 gene encodes a cell surface molecule that assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Synonyms

B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; CD19; CD19

Gene Name

CD19

Gene ID

930

UniProt

P15391

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human CD19, different from the related mouse sequence by seven amino acids.

Clonality

Polyclonal

Tissue Specificity

Widely expressed.

Applications

IHC, WB

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

References & Citations

1. Entrez Gene: CD19 CD19 molecule. 2. Pesando JM, Bouchard LS, McMaster BE (Dec 1989) . CD19 is functionally and physically associated with surface immunoglobulin. The Journal of Experimental Medicine 170 (6) : 2159–64. 3. Tedder TF, Isaacs CM (Jul 1989) . Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily. Journal of Immunology 143 (2) : 712–7.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

64 kDa

Observed Molecular Weight

95 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

B-lymphocyte antigen CD19

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

B-lymphocyte antigen CD19

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.