Anti-S100A11 Antibody Picoband®

About this product

Boster Bio Anti-S100A11 Antibody Picoband® catalog # PB9818. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9818

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

S100 calcium-binding protein A11 (S100A11) is a protein that in humans is encoded by the S100A11 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. And S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.

Synonyms

Protein S100-A11; Calgizzarin; Metastatic lymph node gene 70 protein; MLN 70; Protein S100-C; S100 calcium-binding protein A11; Protein S100-A11, N-terminally processed; S100A11; MLN70, S100C

Gene Name

S100A11

Gene ID

6282

UniProt

P31949

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human S100A11 recombinant protein (Position: A2-T105) . Human S100A11 shares 86.7% amino acid (aa) sequence identity with both mouse and rat S100A11.

Clonality

Polyclonal

Tissue Specificity

Overexpressed in bladder cancer cells (PubMed:17409436) . .

Applications

WB

Field of Research

Calcium Binding Proteins, Calcium Signaling, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Signal Transduction, Signaling Pathway

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Facilitates the differentiation and the cornification of keratinocytes. .

References & Citations

1. Entrez Gene: S100A11 S100 calcium binding protein A11. 2. Sakaguchi, M., Sonegawa, H., Murata, H., Kitazoe, M., Futami, J., Kataoka, K., Yamada, H., Huh, N. S100A11, an (sic) dual mediator for growth regulation of human keratinocytes. Molec. Biol. Cell 19: 78-85, 2008. 3. Wicki R, Marenholz I, Mischke D, Schäfer BW, Heizmann CW (March 1997) . Characterization of the human S100A12 (calgranulin C, p6, CAAF1, CGRP) gene, a new member of the S100 gene cluster on chromosome 1q21.Cell Calcium 20 (6) : 459–64.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

11740 MW

Observed Molecular Weight

15 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Protein S100-A11

Subcellular Location

Cytoplasm . Nucleus .

Protein Name

Protein S100-A11

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.