Anti-CXCL5 Antibody Picoband®

About this product

Boster Bio Anti-CXCL5 Antibody Picoband® catalog # PB9859. Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9859

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

C-X-C motif chemokine 5?or ENA-78 is a?protein?that in humans is encoded by the?CXCL5?gene. The protein encoded by this gene, CXCL5 is a small?cytokine?belonging to the CXC?chemokine?family. It is produced following stimulation of cells with the inflammatory cytokines?interleukin-1?or?tumor necrosis factor-alpha.?Expression of CXCL5 has also been observed ineosinophils, and can be inhibited with the type II?interferon?IFN-γ. This chemokine stimulates the chemotaxis of neutrophils possessing?angiogenic?properties. It elicits these effects by interacting with the cell surface?chemokine receptor?CXCR2.?The?gene?for CXCL5 is encoded on four?exons?and is located on human?chromosome 4?amongst several other CXC chemokine genes.?CXCL5 has been implicated in connective tissue remodelling.?Also, CXCL5 has been described to regulate neutrophil homeostasis.

Synonyms

C-X-C motif chemokine 5; Cytokine LIX; Small-inducible cytokine B5; Cxcl5; Scyb5

Gene Name

Cxcl5

Gene ID

105988538

UniProt

P97885

Host

Rabbit

Reactivity

Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived rat CXCL5 recombinant protein (Position: A38-Q130) . Rat CXCL5 shares 58.7% and 76.3% amino acid (aa) sequence identity with human and mouse CXCL5, respectively.

Clonality

Polyclonal

Tissue Specificity

At least expressed in the lung and trachea.

Applications

ELISA, WB

Field of Research

Atherosclerosis, Cardiovascular, Chemokines, Immunology, Innate Immunity, Macrophage/Inflammation, Vascular Inflammation

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

May participate in the recruitment of inflammatory cells by injured or infected tissue. .

References & Citations

1. Entrez Gene: CXCL5 chemokine (C-X-C motif) ligand 5. 2. Chang MS, McNinch J, Basu R, Simonet S (Nov 1994) . Cloning and characterization of the human neutrophil-activating peptide (ENA-78) gene. J Biol Chem 269 (41) : 25277–82. 3. Persson T, Monsef N, Andersson P, Bjartell A, Malm J, Calafat J, Egesten A (2003) . Expression of the neutrophil-activating CXC chemokine ENA-78/CXCL5 by human eosinophils. Clin. Exp. Allergy 33 (4) : 531–7.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

14263 MW

Observed Molecular Weight

14 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

C-X-C motif chemokine 5

Subcellular Location

Secreted.

Protein Name

C-X-C motif chemokine 5

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.