Anti-GLUT9/SLC2A9 Antibody Picoband®

About this product

Boster Bio Anti-GLUT9/SLC2A9 Antibody Picoband® catalog # PB9891. Tested in Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9891

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Solute carrier family 2, facilitated glucose transporter member 9, also known as SLC2A9, is a protein that in humans is encoded by the SLC2A9 gene. This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. This gene is mapped to 4p16.1. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. This gene transports urate and fructose. It may have a role in the urate reabsorption by proximal tubules. This gene also transports glucose at low rate.

Synonyms

Solute carrier family 2, facilitated glucose transporter member 9; Glucose transporter type 9; GLUT-9; SLC2A9; GLUT9

Gene Name

SLC2A9

Gene ID

56606

UniProt

Q9NRM0

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human GLUT9.

Clonality

Polyclonal

Tissue Specificity

Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Isoform 2 is only detected in the apical membranes of polarized renal tubular cells and placenta. Isoform 1 and isoform 2 are detected in kidney membrane (at protein level) . .

Applications

Flow Cytometry, IF, IHC, WB

Field of Research

Cancer, Channels, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Transport urate and fructose. May have a role in the urate reabsorption by proximal tubules. Also transports glucose at low rate. .

References & Citations

1. Anzai, N., Ichida, K., Jutabha, P., Kimura, T., Babu, E., Jin, C. J., Srivastava, S., Kitamura, K., Hisatome, I., Endou, H., Sakurai, H. Plasma urate level is ly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans. J. Biol. Chem. 283: 26834-26838, 2008. Note: Erratum: J. Biol. Chem. 283: 32152 only, 2008. 2. Preitner, F., Bonny, O., Laverriere, A., Rotman, S., Firsov, D., Da Costa, A., Metref, S., Thorens, B. Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy. Proc. Nat. Acad. Sci. 106: 15501-15506, 2009.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

58702 MW

Observed Molecular Weight

55 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Solute carrier family 2, facilitated glucose transporter member 9

Subcellular Location

Isoform 1: Basolateral cell membrane ; Multi- pass membrane protein .

Protein Name

Solute carrier family 2, facilitated glucose transporter member 9

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.