Anti-GAL4/LGALS4 Antibody Picoband®

About this product

Boster Bio Anti-GAL4/LGALS4 Antibody Picoband® catalog # PB9952. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9952

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Galectin-4 is a protein that in humans is encoded by the LGALS4 gene. This gene is mapped to chromosome 19q13.2 based on an alignment of the LGALS4 sequence. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer. The 323-amino acid LGALS4 protein contains 2 homologous, approximately 150-amino acid carbohydrate recognition domains and all amino acids typically conserved in galectins.

Synonyms

Galectin-4; Gal-4; Antigen NY-CO-27; L-36 lactose-binding protein; L36LBP; Lactose-binding lectin 4; LGALS4

Gene Name

LGALS4

Gene ID

3960

UniProt

P56470

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human GAL4, different from the related mouse and rat sequences by seven amino acids.

Clonality

Polyclonal

Applications

Flow Cytometry, IF, ICC, WB

Field of Research

Cancer, Cell Adhesion,2339, Cytoskeleton/ECM, Energy Metabolism, Energy Transfer Pathways, Epigenetics and Nuclear Signaling, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction, Tags & Cell Markers, Transcription, Transcription Factors

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions.

References & Citations

1. Entrez Gene: LGALS4 lectin, galactoside-binding, soluble, 4 (galectin 4) . 2. Barondes SH, Cooper DN, Gitt MA, Leffler H (Sep 1994) . Galectins. Structure and function of a large family of animal lectins. J Biol Chem 269 (33) : 20807–10. 3. Rechreche, H., Mallo, G. V., Montalto, G., Dagorn, J.-C., Iovanna, J. L. Cloning and expression of the mRNA of human galectin-4, an S-type lectin down-regulated in colorectal cancer. Europ. J. Biochem. 248: 225-230, 1997.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

35941 MW

Observed Molecular Weight

39 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Galectin-4

Subcellular Location

Cytoplasm. Secreted . Exists in three distinct states: free within the cell, released into the extracellular space, or conjugated to target proteins. .

Protein Name

Galectin-4

Isotype

Rabbit IgG

Contents

243