Anti-Alpha 1 Acid Glycoprotein/ORM1 Antibody Picoband®

About this product

Boster Bio Anti-Alpha 1 Acid Glycoprotein/ORM1 Antibody Picoband® catalog # PB9956. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB9956

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Alpha-1-acid glycoprotein 1 is a protein that in humans is encoded by the ORM1 gene. The structural gene for orosomucoid (ORM1) is assigned to the end of the long arm of chromosome 9 by demonstration of linkage to ABO and AK1. This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression.

Synonyms

Alpha-1-acid glycoprotein 1; AGP 1; Orosomucoid-1; OMD 1; ORM1; AGP1

Gene Name

ORM1

Gene ID

5004

UniProt

P02763

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E. coli-derived human ORM1 recombinant protein (Position: Q19-S201) . Human ORM1 shares 47.5% and 48.1% amino acid (aa) sequence identity with mouse and rat ORM1, respectively.

Clonality

Polyclonal

Tissue Specificity

Expressed by the liver and secreted in plasma.

Applications

ELISA, IHC, WB

Field of Research

Cardiovascular, Immunology, Innate Immunity, Macrophage/Inflammation, Secreted Molecules, Serum Proteins

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. .

References & Citations

1. Entrez Gene: ORM1 orosomucoid 1. 2. Boncela, J; Papiewska I; Fijalkowska I; Walkowiak B; Cierniewski C S (Sep 2001) . Acute phase protein alpha 1-acid glycoprotein interacts with plasminogen activator inhibitor type 1 and stabilizes its inhibitory activity. J. Biol. Chem. (United States) 276 (38) : 35305–11. 3. Eiberg, H., Mohr, J., Nielsen, L. S. Linkage of orosomucoid (ORM) to ABO and AK1. (Abstract) Cytogenet. Cell Genet. 32: 272 only, 1982.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

23512 MW

Observed Molecular Weight

40-47 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Alpha-1-acid glycoprotein 1

Subcellular Location

Secreted.

Protein Name

Alpha-1-acid glycoprotein 1

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.