Anti-VIP peptides VIP Antibody

About this product

Boster Bio Anti-VIP peptides VIP Antibody catalog # RP1108. Tested in IF, IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

RP1108

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Vasoactive intestinal peptide, also known as PHM27 or VIP, is a peptide hormone containing 28 amino acid residues. This gene is mapped to 6q25. The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Synonyms

VIP peptides; Intestinal peptide PHV-42; Peptide histidine valine 42; Intestinal peptide PHM-27; Peptide histidine methioninamide 27; Vasoactive intestinal peptide; VIP; Vasoactive intestinal polypeptide; VIP

Gene Name

VIP

Gene ID

7432

UniProt

P01282

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human VIP, different from the related mouse and rat sequences by four amino acids.

Clonality

Polyclonal

Tissue Specificity

Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.

Applications

IF, IHC

Field of Research

Neuropeptides, Neuroscience, Neurotransmitter

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. .

References & Citations

1. Fahrenkrug J, Emson PC (Sep 1982) . Vasoactive intestinal polypeptide: functional aspects. British Medical Bulletin 38 (3) : 265–70. 2. Linder S, Barkhem T, Norberg A, Persson H, Schalling M, Hökfelt T, Magnusson G (Jan 1987) . Structure and expression of the gene encoding the vasoactive intestinal peptide precursor. Proceedings of the National Academy of Sciences of the United States of America 84 (2) : 605–9. 3. Said SI (Apr 1986) . Vasoactive intestinal peptide. Journal of Endocrinological Investigation 9 (2) : 191–200.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

19169 MW

Observed Molecular Weight

26 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

VIP peptides

Subcellular Location

Secreted.

Protein Name

VIP peptides

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.