Anti-RPL19 Antibody Picoband®

About this product

Boster Bio Anti-RPL19 Antibody Picoband® catalog # PB10092. Tested in Flow Cytometry, ICC/IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB10092

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

60S ribosomal protein L19 is a protein that in humans is encoded by the RPL19 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L19E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Synonyms

60S ribosomal protein L19; RPL19

Gene Name

RPL19

Gene ID

6143

UniProt

P84098

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human RPL19, identical to the related mouse and rat sequences.

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma. .

Applications

Flow Cytometry, ICC/IF, IHC, WB

Field of Research

Cancer, Cell Type Markers, DNA/RNA, Epigenetics and Nuclear Signaling, Ribosome, Tags & Cell Markers, Translation, Tumor Associated, Tumor Biomarkers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.

References & Citations

1. Feo S, Davies B, Fried M (Jun 1992) . The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome. Genomics 13 (1) : 201–7. 2. Wool IG, Chan YL, Glück A (1996) . Structure and evolution of mammalian ribosomal proteins..Biochem. Cell Biol. 73 (11-12) : 933–47.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

23466 MW

Observed Molecular Weight

28 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

60S ribosomal protein L19

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Cell junction, adherens junction . Colocalizes with MLLT4 at cadherin-based adherens junctions (PubMed:11544254) .

Protein Name

60S ribosomal protein L19

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.