Anti-MPS1/RPS27 Antibody Picoband®

About this product

Boster Bio Anti-MPS1/RPS27 Antibody Picoband® catalog # PB10093. Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PB10093

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

40S ribosomal protein S27, also known as metallopan-stimulin 1 or MPS-1, is a protein that in humans is encoded by the RPS27 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Synonyms

40S ribosomal protein S27; Metallopan-stimulin 1; MPS-1; RPS27; MPS1

Gene Name

RPS27

Gene ID

6232

UniProt

P42677

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E. coli-derived human MPS1 recombinant protein (Position: P2-H84) . Human MPS1 shares 100% amino acid (aa) sequence identity with both mouse and rat MPS1.

Clonality

Polyclonal

Tissue Specificity

Expressed in a wide variety of actively proliferating cells and tumor tissues.

Applications

Flow Cytometry, IF, IHC, IHC-F, ICC, WB

Field of Research

Cell Biology, DNA/RNA, Epigenetics and Nuclear Signaling, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ribosome, Translation

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

References & Citations

1. Fernandez-Pol JA (1996) . Metallopanstimulin as a novel tumor marker in sera of patients with various types of common cancers: implications for prevention and therapy. Anticancer Research 16 (4B) : 2177–85. 2. Tsui SK, Lee SM, Fung KP, Waye MM, Lee CY (Oct 1996) . Primary structures and sequence analysis of human ribosomal proteins L39 and S27. Biochemistry and Molecular Biology International 40 (3) : 611–6.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

9461 MW

Observed Molecular Weight

10 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

40S ribosomal protein S27

Protein Name

40S ribosomal protein S27

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.