Anti-HDGF Antibody Picoband®

About this product

Boster Bio Anti-HDGF Antibody Picoband® catalog # A01057. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A01057

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Hepatoma-derived growth factor (HDGF), also known as high mobility group protein 1-like 2 (HMG-1L2), is a protein that in humans is encoded by the HDGF gene. This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. And this gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Synonyms

Hepatoma-derived growth factor; HDGF; High mobility group protein 1-like 2; HMG-1L2; HDGF; HMG1L2

Gene Name

HDGF

Gene ID

3068

UniProt

P51858

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human HDGF, identical to the related mouse and rat sequences.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

Flow Cytometry, IF, IHC, ICC, WB

Field of Research

Cancer, Tumor Biomarkers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor. .

References & Citations

1. Entrez Gene: HDGF hepatoma-derived growth factor (high-mobility group protein 1-like) . 2. Everett AD, Bushweller J (2003) . Hepatoma derived growth factor is a nuclear targeted mitogen.. Current drug targets. 4 (5) : 367–71. 3. Wanschura S, Schoenmakers EF, Huysmans C, Bartnitzke S, Van de Ven WJ, Bullerdiek J (May 1997) . Mapping of the gene encoding the human hepatoma-derived growth factor (HDGF) with homology to the high-mobility group (HMG) -1 protein to Xq25. Genomics. 32 (2) : 298–300.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

26788 MW

Observed Molecular Weight

38 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Hepatoma-derived growth factor

Subcellular Location

Cytoplasm. Nucleus.

Protein Name

Hepatoma-derived growth factor

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.