Anti-Dishevelled 3/DVL3 Antibody Picoband®

About this product

Boster Bio Anti-Dishevelled 3/DVL3 Antibody Picoband® catalog # A03577. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A03577

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Segment polarity protein dishevelled homolog DVL-3 is a protein that in humans is encoded by the DVL3 gene. It is mapped to 3q27.1. This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.

Synonyms

Segment polarity protein dishevelled homolog DVL-3; Dishevelled-3; DSH homolog 3; DVL3; KIAA0208

Gene Name

DVL3

Gene ID

1857

UniProt

Q92997

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Dishevelled 3, identical to the related mouse sequence.

Clonality

Polyclonal

Applications

WB

Field of Research

Cardiogenesis, Cardiovascular, Cytoplasmic, Neurogenesis, Neurology Process, Neuroscience, Signaling Pathways, Stem Cells

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

May play a role in the signal transduction pathway mediated by multiple Wnt genes.

References & Citations

1. Hocevar, B A; Mou F; Rennolds J L; Morris S M; Cooper J A; Howe P H (June 2003) . Regulation of the Wnt signaling pathway by disabled-2 (Dab2) . EMBO J. England. 22 (12) : 3084–94. 2. Pizzuti A, Amati F, Calabrese G, Mari A, Colosimo A, Silani V, Giardino L, Ratti A, Penso D, Calza L, Palka G, Scarlato G, Novelli G, Dallapiccola B (January 1997) . cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene. Hum Mol Genet. 5 (7) : 953–8.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

78055 MW

Observed Molecular Weight

78 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Segment polarity protein dishevelled homolog DVL-3

Subcellular Location

Cytoplasm .

Protein Name

Segment polarity protein dishevelled homolog DVL-3

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.