Anti-NOV/CCN3 Antibody Picoband®

About this product

Boster Bio Anti-NOV/CCN3 Antibody Picoband® catalog # A06319-1. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A06319-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

NOV (nephroblastoma overexpressed), also known as CCN3, is a matricellular protein that in humans is encoded by the NOV gene. The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development.

Synonyms

Protein NOV homolog; NovH; CCN family member 3; Insulin-like growth factor-binding protein 9; IBP-9; IGF-binding protein 9; IGFBP-9; Nephroblastoma-overexpressed gene protein homolog; NOV; CCN3, IGFBP9, NOVH

Gene Name

NOV

Gene ID

4856

UniProt

P48745

Host

Rabbit

Reactivity

Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human NOV/CCN3, different from the related mouse sequence by seven amino acids, and from the related rat sequence by four amino acids.

Clonality

Polyclonal

Tissue Specificity

Expressed in bone marrow, thymic cells and nephroblastoma. Increased expression in Wilms tumor of the stromal type. .

Applications

Flow Cytometry, IF, IHC, ICC, WB

Field of Research

DNA/RNA, Epigenetics and Nuclear Signaling, RNA Processing

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Immediate-early protein likely to play a role in cell growth regulation. .

References & Citations

1. Jun JI, Lau LF (Dec 2011) . Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets. Nature Reviews. Drug Discovery. 10 (12) : 945–63. 2. Martinerie C, Viegas-Pequignot E, Guenard I, Dutrillaux B, Nguyen VC, Bernheim A, Perbal B (Dec 1992) . Physical mapping of human loci homologous to the chicken nov proto-oncogene. Oncogene. 7 (12) : 2529–34.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

39162 MW

Observed Molecular Weight

47 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Protein NOV homolog

Subcellular Location

Secreted.

Protein Name

AP-2 complex subunit mu

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.