Anti-SLC7A3 Antibody Picoband®

About this product

Boster Bio Anti-SLC7A3 Antibody Picoband® catalog # A09720-1. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A09720-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Cationic amino acid transporter 3 is a protein that in humans is encoded by the SLC7A3 gene. This gene encodes a member of the solute carrier family 7. The encoded protein is a sodium-independent cationic amino acid transporter. Alternate splicing results in multiple transcripts that encoded the same protein. The International Radiation Hybrid Mapping Consortium mapped the SLC7A3 gene to the X chromosome.

Synonyms

Cationic amino acid transporter 3; CAT-3; CAT3; Cationic amino acid transporter y+; Solute carrier family 7 member 3; SLC7A3; ATRC3, CAT3

Gene Name

SLC7A3

Gene ID

84889

UniProt

Q8WY07

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human SLC7A3, different from the related mouse and rat sequences by four amino acids.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala. .

Applications

WB

Field of Research

Amino Acid Metabolism, Amino Acids, Cancer, Channels, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner. .

References & Citations

1. Ito K, Groudine M (1997) . A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain.. J. Biol. Chem. 272 (42) : 26780–6. 2. Gilles W, Vulcu SD, Liewald JF, et al. (2005) . Monovalent cation conductance in Xenopus laevis oocytes expressing hCAT-3.. Biochim. Biophys. Acta.1668 (2) : 234–9. 3. Vekony, N., Wolf, S., Boissel, J.-P., Gnauert, K., Closs, E. I. Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues. Biochemistry 40: 12387-12394, 2001.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

67169 MW

Observed Molecular Weight

67 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Cationic amino acid transporter 3

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Isotype

Rabbit IgG

Contents

243