Anti-Relaxin 1/RLN1 Antibody Picoband®

About this product

Boster Bio Anti-Relaxin 1/RLN1 Antibody Picoband® catalog # A08367-1. Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A08367-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Relaxin 1 is a member of relaxin-like peptide family. Relaxin gene maps to human chromosome 19 near D19Mit23. Relaxin is a peptide hormone produced by the corpora lutea of ovaries during pregnancy in many mammalian species, including man. Relaxin widens the pubic bone and facilitates labor, it also softens the cervix (cervical ripening), and relaxes the uterine musculature. However, its significance may reach much further. Relaxin affects collagen metabolism, inhibiting collagen synthesis and enhancing its breakdown by increasing matrix metalloproteinases. It also enhances angiogenesis and is a potent renal vasodilator.

Synonyms

Prorelaxin H1; Relaxin B chain; Relaxin A chain; RLN1

Gene Name

RLN1

Gene ID

6013

UniProt

P04808

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Relaxin 1, which shares 45.2% amino acid (aa) sequence identity with mouse Relaxin 1.

Clonality

Polyclonal

Tissue Specificity

Prostate. Not expressed in placenta, decidua or ovary.

Applications

IHC, WB

Field of Research

Cell Type Markers, Growth Factors/Hormones, Signal Transduction, Tags & Cell Markers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.

References & Citations

1. Hsu, S. Y., Nakabayashi, K., Nishi, S., Kumagai, J., Kudo, M., Sherwood, O. D., Hsueh, A. J. W. Activation of orphan receptors by the hormone relaxin. Science 295: 671-674, 2002. 2. Schwabe, C., Bullesbach, E. E. Relaxin: structures, functions, promises, and nonevolution. FASEB J. 8: 1152-1160, 1994.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

21 kDa

Specificity

No cross reactivity with other proteins.

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.