Anti-NAP2/Ppbp Antibody Picoband®

About this product

Boster Bio Anti-NAP2/Ppbp Antibody Picoband® catalog # A02736. Tested in IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A02736

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Chemokine (C-X-C motif) ligand 7 (CXCL7), also known as NAP2 or Pro-Platelet basic protein (PPBP), is a human gene. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Furthermore, the protein is an antimicrobial protein with bactericidal and antifungal activity.

Synonyms

Chemokine (C-X-C motif) ligand 7, isoform CRA_b ; Chemokine subfamily B Cys-X-Cys ; Platelet basic protein ; Pro-platelet basic protein ; Putative uncharacterized protein ; Thymus chemokine 1 ; Ppbp ; Cxcl7 ; mCG_1702

Gene Name

Ppbp

Gene ID

57349

UniProt

Q9EQI5

Host

Rabbit

Reactivity

Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived mouse NAP2 recombinant protein (Position: K40-Y113) .

Clonality

Polyclonal

Applications

IHC, WB

Field of Research

Cardiovascular, Chemokines, Immunology, Innate Immunity, Platelets

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

References & Citations

1. Entrez Gene: PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) . 2. Hristov M, Zernecke A, Bidzhekov K; et al. (March 2007) . Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury.Circ. Res. 100 (4) : 590–7. 3. Majumdar S, Gonder D, Koutsis B, Poncz M (1991) . Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4. J Biol Chem 266 (9) : 5785–9.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

12252 MW

Observed Molecular Weight

11 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Pro-platelet basic protein

Isotype

Rabbit IgG

Contents

243