Anti-TAPA1/Cd81 Antibody Picoband®

About this product

Boster Bio Anti-TAPA1/Cd81 Antibody Picoband® catalog # A01281-3. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A01281-3

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD81 molecule, also known as CD81 (Cluster of Differentiation 81), is a protein which in humans is encoded by the CD81 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; CD81; Cd81; Tapa1

Gene Name

Cd81

Gene ID

12520

UniProt

P35762

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived mouse TAPA1 recombinant protein (Position: K116-K201) .

Clonality

Polyclonal

Tissue Specificity

Expressed in oocytes. Highly expressed in granulosa cells.

Applications

ELISA, IF, IHC, WB

Field of Research

Adaptive Immunity, B Cells, Host-Virus Interaction, Human Protein, Immunology, Interspecies Interaction, Microbiology, Protein

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

May play an important role in the regulation of lymphoma cell growth. May be involved in the acrosome reaction.

References & Citations

1. Andria ML, Hsieh CL, Oren R, Francke U, Levy S (August 1991) .Genomic organization and chromosomal localization of the TAPA-1 gene.Journal of Immunology. 147 (3) : 1030–6. 2. Levy S, Todd SC, Maecker HT (1998) . CD81 (TAPA-1) : a molecule involved in signal transduction and cell adhesion in the immune system..Annu Rev Immunol. 16: 89–109.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

22 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

CD81 antigen

Subcellular Location

Basolateral cell membrane.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.