Anti-Galanin Antibody Picoband®

About this product

Boster Bio Anti-Galanin Antibody Picoband® catalog # A00606-1. Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A00606-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Galanin is a neuropeptide encoded by the GAL gene, that is widely expressed in the brain, spinal cord, and gut of humans as well as other mammals. This gene encodes a neuroendocrine peptide that is widely expressed in the central and peripheral nervous systems and also the gastrointestinal tract, pancreas, adrenal gland and urogenital tract. The encoded protein is a precursor that is proteolytically processed to generate two mature peptides: galanin and galanin message-associated peptide (GMAP) . Galanin has diverse physiological functions including nociception, feeding and energy homeostasis, osmotic regulation and water balance. GMAP has been demonstrated to possess antifungal activity and hypothesized to be part of the innate immune system.

Synonyms

Galanin peptides; Galanin; Galanin message-associated peptide; GMAP; GAL; GAL1; GALN; GLNN

Gene Name

GAL

Gene ID

51083

UniProt

P22466

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Galanin, which shares 86.2% amino acid (aa) sequence identity with both mouse and rat Galanin.

Clonality

Polyclonal

Applications

WB

Field of Research

Epigenetics and Nuclear Signaling, Mediator Complex, Transcription

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.

References & Citations

1. Mitsukawa K, Lu X, Bartfai T (June 2008) . Galanin, galanin receptors and drug targets. Cell. Mol. Life Sci. 65 (12) : 1796–805. 2. Wu Z, Autry AE, Bergan JF, Watabe-Uchida M, Dulac CG (May 2014) .Galanin neurons in the medial preoptic area govern parental behaviour. Nature. 509 (7500) : 325–30.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

19 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Galanin and GMAP prepropeptide

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

243