Anti-TCP1 eta/CCT7 Antibody Picoband®

About this product

Boster Bio Anti-TCP1 eta/CCT7 Antibody Picoband® catalog # A08169-2. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A08169-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

T-complex protein 1 subunit eta is a protein that in humans is encoded by the CCT7 gene. This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.

Synonyms

T-complex protein 1 subunit eta; TCP-1-eta; CCT-eta; HIV-1 Nef-interacting protein; T-complex protein 1 subunit eta, N-terminally processed; CCT7; CCTH; NIP7-1

Gene Name

CCT7

Gene ID

10574

UniProt

Q99832

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human CCT7 recombinant protein (Position: Q30-D307) .

Clonality

Polyclonal

Applications

ELISA, Flow Cytometry, IF, ICC, WB

Field of Research

Immune System Diseases, Immunology, Protein Trafficking, Signal Transduction, Signaling Pathway

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity) . .

References & Citations

1. Entrez Gene: CCT7 chaperonin containing TCP1, subunit 7 (eta) . 2. Won KA, Schumacher RJ, Farr GW, Horwich AL, Reed SI (Dec 1998) . Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT. Molecular and Cellular Biology. 18 (12) : 7584–9.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

59 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Chaperonin containing TCP1 subunit 7

Subcellular Location

Cytoplasm.

Isotype

Rabbit IgG

Contents

243