Anti-CD200/OX2 Antibody Picoband®

About this product

Boster Bio Anti-CD200/OX2 Antibody Picoband® catalog # A01512-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A01512-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

OX-2 membrane glycoprotein, also named CD200 (Cluster of Differentiation 200) is a human protein encoded by the CD200 gene. The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.

Synonyms

OX-2 membrane glycoprotein; CD200; MOX1; MOX2; My033

Gene Name

CD200

Gene ID

4345

UniProt

P41217

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human CD200/OX2 recombinant protein (Position: Q31-K231) .

Clonality

Polyclonal

Tissue Specificity

Brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. Preferentially expressed in fetal brain.

Applications

WB, ELISA

Field of Research

Adaptive Immunity, Atherosclerosis, Cardiovascular, Immunology, T Cells, Vascular Inflammation

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.

References & Citations

1. Entrez Gene: CD200 CD200 molecule. 2. Hoek RM, Ruuls SR, Murphy CA, et al. (2000) . Down-regulation of the macrophage lineage through interaction with OX2 (CD200) . Science. 290 (5497) : 1768–71. 3. Wright GJ, Jones M, Puklavec MJ, et al. (2001) . The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans. Immunology. 102 (2) : 173–9.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

45 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

CD200 molecule

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Name

Ephrin type-B receptor 2

Isotype

Rabbit IgG

Contents

243