Anti-Creatine kinase B type/CKB Antibody Picoband®

About this product

Boster Bio Anti-Creatine kinase B type/CKB Antibody Picoband® catalog # A01695-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A01695-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Brain-type creatine kinase also known as CK-BB is a creatine kinase that in humans is encoded by the CKB gene. The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized.

Synonyms

Creatine kinase B-type; B-CK; Creatine kinase B chain; CKB; CKBB

Gene Name

CKB

Gene ID

1152

UniProt

P12277

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human CKB recombinant protein (Position: H7-K381) .

Clonality

Polyclonal

Applications

ELISA, IHC, WB

Field of Research

Cancer, Cell Biology, Oncoproteins, Oncoproteins/Suppressors, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ring Finger E3 Ligase, Tumor Antigens, Tumor Biomarkers, Tumor Immunology, Tumor-Associated Antigens, Ubiquitin E3 Enzymes

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate) . Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

References & Citations

1. Mariman EC, Schepens JT, Wieringa B (August 1989) . Complete nucleotide sequence of the human creatine kinase B gene. Nucleic Acids Res. 17 (15) : 6385. 2. Benger, J. C., Teshima, I., Walter, M. A., Brubacher, M. G., Daouk, G. H., Cox, D. W. Localization and genetic linkage of the human immunoglobulin heavy chain genes and the creatine kinase brain (CKB) gene: identification of a hot spot for recombination. Genomics 9: 614-622, 1991.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

45 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Creatine kinase B

Subcellular Location

Cytoplasm.

Isotype

Rabbit IgG

Contents

243