Anti-GDA Antibody Picoband®

About this product

Boster Bio Anti-GDA Antibody Picoband® catalog # A01619-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A01619-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Guanine deaminase also known as cypin, guanase, guanine aminase, GAH, and guanine aminohydrolase is an aminohydrolase enzyme which converts guanine to xanthine. This gene is mapped to 9q21.13. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

Guanine deaminase; Guanase; Guanine aminase; Guanine aminohydrolase; GAH; p51-nedasin; GDA; KIAA1258

Gene Name

GDA

Gene ID

9615

UniProt

Q9Y2T3

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human GDA recombinant protein (Position: E220-Q446) .

Clonality

Polyclonal

Tissue Specificity

Expressed in lung carcinoma cell lines but not in normal lung tissues.

Applications

ELISA, IHC, WB

Field of Research

Chromatin Modifying Enzymes, DNA/Nucleotides, DNA/RNA, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. .

References & Citations

1. Akum, B. F., Chen, M., Gunderson, S. I., Riefler, G. M., Scerri-Hansen, M. M., Firestein, B. L. Cypin regulates dendrite patterning in hippocampal neurons by promoting microtubule assembly. Nature Neurosci. 7: 145-152, 2004. 2. Yuan, G., Bin, J. C., McKay, D. J., Snyder, F. F. Cloning and characterization of human guanine deaminase: purification and partial amino acid sequence of the mouse protein. J. Biol. Chem. 274: 8175-8180, 1999.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

51 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Guanine deaminase

Subcellular Location

Nucleus.

Isotype

Rabbit IgG

Contents

243