Anti-IL32 Antibody Picoband®

About this product

Boster Bio Anti-IL32 Antibody Picoband® catalog # A03286. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A03286

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Interleukin 32 (Il32) is a protein that in humans is encoded by the IL32 gene. This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms

Interleukin-32; IL-32; Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor; IL32; NK4; TAIF

Gene Name

IL32

Gene ID

9235

UniProt

P24001

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human IL32 recombinant protein (Position: A31-K234) .

Clonality

Polyclonal

Tissue Specificity

Selectively expressed in lymphocytes. Expression is more prominent in immune cells than in non-immune cells.

Applications

ELISA (Cap), WB

Field of Research

Autoimmune, Cancer, Cytokines, Immune System Diseases, Immunology, Innate Immunity, Interleukins, Tumor Immunology

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF- alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK.

References & Citations

1. Kim SH, Han SY, Azam T, Yoon DY, Dinarello CA (January 2005) . Interleukin-32: a cytokine and inducer of TNFalpha. Immunity. 22 (1) : 131–42. 2. Mabilleau G, Sabokbar A (2009) . Interleukin-32 promotes osteoclast differentiation but not osteoclast activation. PLoS ONE. 4 (1) : e4173.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

27683 MW

Observed Molecular Weight

19 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Interleukin 32

Subcellular Location

Secreted.

Protein Name

CD48 antigen

Isotype

Rabbit IgG

Contents

243