Anti-Protein S/PROS1 Antibody Picoband®

About this product

Boster Bio Anti-Protein S/PROS1 Antibody Picoband® catalog # A01568-1. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A01568-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

This PROS1 gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

Synonyms

Vitamin K-dependent protein S; PROS1; PROS

Gene Name

PROS1

Gene ID

5627

UniProt

P07225

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human Protein S recombinant protein (Position: L291-S676) .

Clonality

Polyclonal

Tissue Specificity

Plasma.

Applications

WB, ELISA

Field of Research

Cardiovascular, Serum Proteins

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.

References & Citations

1. Long GL, Marshall A, Gardner JC, Naylor SL (January 1988) . Genes for human vitamin K-dependent plasma proteins C and S are located on chromosomes 2 and 3, respectively. Somat. Cell Mol. Genet. 14 (1) : 93–8. 2. Dahlbäck B, Lundwall A, Stenflo J (Jun 1986) . Primary structure of bovine vitamin K-dependent protein S. Proceedings of the National Academy of Sciences. 83 (12) : 4199–203.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

28681 MW

Observed Molecular Weight

75 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Protein S

Subcellular Location

Secreted.

Protein Name

40S ribosomal protein S6

Isotype

Rabbit IgG

Contents

243