Anti-Steroid sulfatase/STS Antibody Picoband®

About this product

Boster Bio Anti-Steroid sulfatase/STS Antibody Picoband® catalog # A01198-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A01198-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Steroid sulfatase (STS), or steryl-sulfatase, formerly known as arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids. It is encoded by the STS gene. This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI) . Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene.

Synonyms

Steryl-sulfatase; Arylsulfatase C; ASC; Steroid sulfatase; Steryl-sulfate sulfohydrolase; STS; ARSC1

Gene Name

STS

Gene ID

412

UniProt

P08842

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human Steroid sulfatase recombinant protein (Position: K297-E396) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine. .

Applications

ELISA, Flow Cytometry, WB

Field of Research

Adapters, Adaptive Immunity, Cell Biology, Immunology, Proteasome / Ubiquitin, Protein Trafficking, Proteolysis/Ubiquitin, Signal Transduction, T Cells, Vesicle Transport

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Conversion of sulfated steroid precursors to estrogens during pregnancy.

References & Citations

1. Entrez Gene: STS steroid sulfatase (microsomal), arylsulfatase C, isozyme S. 2. Alperin ES, Shapiro LJ (August 1997) . Characterization of point mutations in patients with X-linked ichthyosis. Effects on the structure and function of the steroid sulfatase protein. The Journal of Biological Chemistry. 272 (33) : 20756–63. 3. Rižner TL (2016) . The Important Roles of Steroid Sulfatase and Sulfotransferases in Gynecological Diseases. Frontiers in Pharmacology. 7: 30.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

21405 MW

Observed Molecular Weight

65 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Steroid sulfatase

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Protein Name

Cytoglobin

Isotype

Rabbit IgG

Contents

243