Anti-BAFF Receptor/Tnfrsf13c Antibody Picoband®

About this product

Boster Bio Anti-BAFF Receptor/Tnfrsf13c Antibody Picoband® catalog # A02865-2. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A02865-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFFR, is a protein in humans is encoded by the TNFRSF13C gene. The BAFFR gene is mapped to chromosome 22q13.1-q13.31. It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein. B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.

Synonyms

Tumor necrosis factor receptor superfamily member 13C; B-cell maturation defect; B-cell-activating factor receptor; BAFF receptor; BAFF-R; BLyS receptor 3; CD268; Tnfrsf13c; Baffr; Bcmd; Br3

Gene Name

Tnfrsf13c

Gene ID

72049

UniProt

Q9D8D0

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived mouse BAFF Receptor recombinant protein (Position: M1-A71) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in spleen and testis; detected at lower levels in lung and thymus.

Applications

ELISA, WB

Field of Research

Growth Factors/Hormones, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.

References & Citations

1. Thompson JS, Bixler SA, Qian F, Vora K, Scott ML, Cachero TG, Hession C, Schneider P, Sizing ID, Mullen C, Strauch K, Zafari M, Benjamin CD, Tschopp J, Browning JL, Ambrose C (Sep 2001) . BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 293 (5537) : 2108–11. 2. “Entrez Gene: TNFRSF13C tumor necrosis factor receptor superfamily, member 13C. 3. Schiemann, B., Gommerman, J. L., Vora, K., Cachero, T. G., Shulga-Morskaya, S., Dobles, M., Frew, E., Scott, M. L.An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway.Science293: 2111-2114, 2001.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

19 kDa, 40 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Tumor necrosis factor receptor superfamily, member 13c

Subcellular Location

Membrane; Single-pass type III membrane protein.

Isotype

Rabbit IgG

Contents

243