Anti-MUC7 Antibody Picoband®

About this product

Boster Bio Anti-MUC7 Antibody Picoband® catalog # A05210. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A05210

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Mucin-7 is a protein that in humans is encoded by the MUC7 gene. This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acids. This antimicrobial protein has antibacterial and antifungal activity. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.

Synonyms

Mucin-7; MUC-7; Apo-MG2; Salivary mucin-7; MUC7; MG2

Gene Name

MUC7

Gene ID

4589

UniProt

Q8TAX7

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human MUC7.

Clonality

Polyclonal

Tissue Specificity

Expressed in salivary gland tissues and only in those that contain mucous acinar cells (e.g. sublingual and submandibular glands) and not in salivary glands containing only serous acinar cells (e.g. parotid gland) .

Applications

WB

Field of Research

Cancer, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Immunology, Invasion/Microenvironment, Secreted Molecules, Signal Transduction, Tumor Biomarkers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili.

References & Citations

1. Entrez Gene: MUC7 mucin 7, secreted. 2. Bobek LA, Liu J, Sait SN, Shows TB, Bobek YA, Levine MJ (Mar 1997) . Structure and chromosomal localization of the human salivary mucin gene, MUC7. Genomics. 31 (3) : 277–82.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

39411 MW

Observed Molecular Weight

46 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Mucin 7, secreted

Subcellular Location

Secreted.

Protein Name

Long-chain-fatty-acid--CoA ligase 5

Isotype

Rabbit IgG

Contents

243