Anti-Tryptophan Hydroxylase/TPH1 Antibody Picoband®

About this product

Boster Bio Anti-Tryptophan Hydroxylase/TPH1 Antibody Picoband® catalog # A01626-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A01626-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the TPH1 gene. This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.

Synonyms

Tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1; TPH1; TPH; TPRH; TRPH

Gene Name

TPH1

Gene ID

7166

UniProt

P17752

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human Tryptophan Hydroxylase recombinant protein (Position: M1-K111) .

Clonality

Polyclonal

Tissue Specificity

Isoform 2 seems to be less widely expressed than isoform 1.

Applications

ELISA, WB

Field of Research

Amino Acid Metabolism, Amino Acids, Cancer, Cancer Metabolism, Endocrine Metabolism, Energy Metabolism, Energy Transfer Pathways, Hormone Biosynthesis, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Neuroscience, Neurotransmitter, Pathways and Processes, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

References & Citations

1. Entrez Gene: TPH1 tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) . 2. New AS, Gelernter J, Yovell Y, Trestman RL, Nielsen DA, Silverman J, Mitropoulou V, Siever LJ (1998) . Tryptophan hydroxylase genotype is associated with impulsive-aggression measures: a preliminary study. Am. J. Med. Genet. 81 (1) : 13–7.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

51 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Tryptophan hydroxylase 1

Isotype

Rabbit IgG

Contents

243