Anti-Cardiac FABP Fabp3 Antibody Picoband® (monoclonal, 6C4)

About this product

Boster Bio Anti-Cardiac FABP Fabp3 Antibody Picoband® (monoclonal, 6C4) catalog # M01734. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

M01734

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Heart-type fatty acid binding protein (hFABP), also known as mammary-derived growth inhibitor, is a protein that in humans is encoded by the FABP3 gene. The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is also a candidate tumor suppressor gene for human breast cancer. Cardiac-type fatty acid-binding protein (cFABP) from human heart muscle of three individuals was isolated and characterized as pI 5.3-cFABP.

Synonyms

Fatty acid-binding protein, heart; Fatty acid-binding protein 3; Heart-type fatty acid-binding protein; H-FABP; Fabp3

Gene Name

Fabp3

Gene ID

79131

UniProt

P07483

Host

Mouse

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived rat Cardiac FABP recombinant protein (Position: A2-A133) .

Clonality

Monoclonal

Clone

Clone: 6C4

Tissue Specificity

Heart, but also skeletal muscle, kidney, brain and mammary gland.

Applications

ELISA (Cap), IHC, WB

Field of Research

Cardiovascular, Fatty Acid Oxidation, Fatty Acids, Lipid and Lipoprotein Metabolism, Lipids/Lipoproteins, Mesenchymal Stem Cells, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Redox Metabolism, Stem Cells

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.

References & Citations

1. Entrez Gene: FABP3 fatty acid binding protein 3, muscle and heart (mammary-derived growthinhibitor) . 2. Borchers, T., Hojrup, P., Nielsen, S. U., Roepstorff, P., Spener, F., Knudsen, J. Revision of the amino acid sequence of human heart fatty acid binding protein. Molec. Cell. Biochem. 98: 127-133, 1990. 3. Phelan CM, Larsson C, Baird S, Futreal PA, Ruttledge MH, Morgan K, Tonin P, Hung H, Korneluk RG, Pollak MN, Narod SA (Dec 1996) . The human mammary-derived growth inhibitor (MDGI) gene: genomic structure and mutation analysis in human breast tumors. Genomics 34 (1) : 63–8.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

15 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Fatty acid binding protein 3

Subcellular Location

Cytoplasm.

Protein Name

Activating transcription factor 1

Isotype

Mouse IgG1

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.